LPN1&2 and LEMP

Genetic Testing for neurological diseases  in Leonbergers

LPN/LEMP  Test Results Laboklin.

Attention:
Laboklin states in its test results lette: LPN2 Trait of inheritance: autosomal-recessive”.
This is a faulty  statement.
LPN2 is “A dominant inherited form of PN with incomplete penetrance”.
Update 11 July 2019: Laboklin has corrected the interpretation on the result form.

Vetsuisse Bern offers on its order form a genetic test for sand coat color.
Sand coat color is an officially allowed coat color for Leonbergers.
There is no need to exclude sand coloured Leonbergers from breeding.

Click for LPN-test  interpretation and breeding recomandations.

Click for LPN poster


For LEMP we recommend avoiding matings that could produce LEMP-D/D (i.e. affected) dogs. Having only one LEMP-D/N parent, with a LEMP-N/N parent, will ensure that no LEMP-D/D offspring will be born.
In a global group of more than 5,000 Leonbergers which have been submitted to our laboratories, about 14% were
LEMP-D/ N carriers.

There is no need for a new blood sample if a sample has already been submitted to the Institute of Genetics of the University of Bern for LPN testing, as the LEMP test can be performed on this same sample for 50 CHF/EUR after pre-payment onto the account of the Institute of Genetics (University of Bern):IBAN: CH5309000000603151885, BIC: POFICHBE (Postfinance, CH-3030 Bern).Please mention the lab ID (LB no.) and send an e-mail to:cord.droegemueller@vetsuisse.unibe.ch

LEMP result of dogs that were allready tested for LPN can be  asked by email to 
cord.droegemueller@vetsuisse.unibe.ch -- for dogs tested in Bern,costs € 50,-- per dog.

For dogs tested in Minnesota you can request the LEMP result on https://docs.google.com/forms/d/e/1FAIpQLScdZyTLqAB2XKsD3qEz3mTxRIuX4ibCH8ODVPknos2qYXlHxg/viewform

Order forms LPN_LEMP tests Bern University

Order form  LPN & LEMP and info University of Minnesota

The LPN1 research manuscript was published on October 3, 2014:
http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004635

The LPN2 research manuscript was published in August 2017
click here

Click for the LEMP manuscript